Professor Mone Zaidi

Professor Mone Zaidi obtained an MBBS from King George’s Medical College, India. He trained clinically and obtained a PhD from the Hammersmith Hospital where he was also appointed as Lecturer. He was Senior Lecturer and Consultant at St. Georges Hospital Medical School, before being recruited to Mount Sinai School of Medicine, New York, as Professor of Medicine. He is currently The Mount Sinai Professor of Clinical Medicine, and Director of the Center for Translational Medicine and Pharmacology. Professor Zaidi’s studies, spanning over 30 years, have included the description of calcium sensing in bone cells and the discovery that nitric oxide acts on bone. In 2003, his group published the first evidence for a direct action of pituitary hormones, such as FSH, on the skeleton. He found that inhibiting FSH action not only increased bone mass, but also reduced body fat and prevented neurodegeneration—laying the foundation for a single anti–FSH therapeutic to treat osteoporosis, obesity, and Alzheimer’s disease. This corpus of work was selected by Nature Medicine as one of eight “Notable Advances” in biomedicine for 2017. His work constitutes over 460 publications in journals, including Cell, Nature and PNAS. He currently serves as Deputy Editor for eLife, where he leads the journal’s medical sciences portfolio.