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Name:
Dr R. John Dobbs MC FRCP FBPhS
Organisation:
Institute of Pharmaceutical Science, King’s College London
Year elected:
2012
Primary professional setting:
Academia
Graduated in medicine from the University of Manchester. Trained in Clinical Pharmacology, UCL (BNC Prichard, JW Black) and St George’s (HP Rang) Later Consultant Physician MRC Clinical Research Centre, Harrow. Currently Senior Clinical Researcher, KCL. The aim, with Sylvia Dobbs, is an aetiopathogenic model for Parkinson’s disease (PD) and co-morbidities, taking into account the pre-clinical/prodromal ‘submerged iceberg’. We go beyond clinical diagnostic/severity scores, extending measures of facets, objective where possible, into ‘controls’. (We have evidence that PD-probands’ spouses are down-the-way towards PD.)We are using quantitative metagenomics to investigate species/strains with altered abundance associated with disease facets, metabolomics and immunobiology to define putative mediators/pathways, stratifying for human risk/immune-inflammatory genetics.