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Deep generative molecular design – AI at the service of the drug designer

Artificial intelligence (AI) is an astonishingly rapidly growing technology and is already ‘changing the game’ in many fields. Together with Big Data, AI has been called the fourth industrial revolution. There is no single day when AI does not reveal itself in some form; from...

Of Fangs and Pharmacology: A Deadly Cure for Heart Disease

The following article by Josh Dignam of the William Harvey Research Institute was selected by a panel of judges as the winner of Pharmacology Matters’ first writing prize for Early Career Researchers. Entrants were tasked with writing entertaining, original articles which cou...

Pharmacologist in Phrame: Abhinav Vepa

Pharmacology Matters editor, Aisah Aubdool, interviews Dr Abhinav Vepa about his studies and research. Hello Dr Vepa, and welcome to Pharmacologist in Phrame! What is your background and career pathway to date? After completing school at Queen Elizabeth’s Grammar Schoo...

Footballer to Biotech Entrepreneur: Redefining success to secure a rewarding career

Introduction Dr Darrin M Disley, CEO of Mogrify, knows his way around a football field. A serial biotech entrepreneur, Darrin was once told that he wasn’t good enough to study chemistry, so he momentarily chose football. Fast forward to 2020 and Darrin is an incredibly ...

Meet the Early Career Researcher prize winners for 2020

Each year the British Journal of Pharmacology (BJP) and the British Journal of Clinical Pharmacology (BJCP) award prizes for the best paper published by an early career researcher in the journals over the previous year.   In 2020, the winner for BJP was Yi Wang (YW) of Zh...

The importance of research integrity

What is research integrity? Research integrity is defined as conducting research in a manner that enables the audience to have the utmost confidence and trust in the findings and data presented. Research integrity is essential for conducting scientific research. As ...

Great Expectations: Forming a framework for postgraduate pharmacology

What does it mean to be a master of pharmacology? The Genes, Drugs and Stem Cells (GDS): Novel Therapies MSc at Imperial College London, is a popular choice of taught Master’s course for students from around the world. The course combines learning about advanced therapies,...

A sense of achievement: The Nobel Prize winning discoveries of the temperature and touch receptors

On 4 October 2021, the Nobel Committee announced that Professors David Julius and Ardem Patapoutian had won the 2021 Nobel Prize for Physiology and Medicine for their ground-breaking discoveries of the TRPV1, TRPM8 and Piezo ion channels involved in pain, heat, and touch sens...

‘Where does [my] anxiety come from? The world!’ Trans and gender diverse mental health

Trans and gender diverse people in the UK are in the midst of a national healthcare crisis. The NHS currently has a maximum waiting time for non-urgent referrals of 18 weeks , yet current waiting times for trans and gender diverse patients seeking support and gender related ...

Appreciating the Sexy Side of Experimental Design

A new funding requirement from the Medical Research Council (MRC) came into play from September 2022, necessitating that both sexes are incorporated into the experimental design of grant applications involving animals, tissues and (non-immortalised) cells. This initiative w...