The effect of prostaglandin D₂ on the blood vessels of the perfused isolated cotyledon of the human placenta

Prostaglandin D₂ was shown to constrict the blood vessels of the isolated perfused cotyledon of the human placenta. Its potency was less than that of prostaglandin F_2α but similar to prostaglandin E₂. As it is known to dilate uterine blood vessels it may, by its differential action on the foetal and maternal vascular beds, play a role in the local regulation of utero‐placental blood flow.

DOI: 10.1111/j.1476-5381.1984.tb10737.x

View this article

• Full article (html)
• Enhanced article (html)
• PDF
• References