Article date: June 1982
By: D.F. EVANS, G.E. FOSTER, J.D. HARDCASTLE, F. JOHNSON, J.W. WRIGHT in Volume 76, Issue 2, pages 245-252
Intravenous bolus doses of porcine glucagon of 0.001 −0.05 mg kg−1 caused intense stimulation of the duodenum and jejunum of the dog.
Intravenous infusion of porcine glucagon at 0.025 −0.05 mg kg−1 h−1 caused similar stimulation. In both cases the stimulation was phasic in nature.
Stimulation of the duodenum and jejunum following glucagon was accompanied by a decrease in frequency of the intestinal basic electrical rhythm (BER). No change was seen in the intervals between successive periods of phase III motor activity.
Intravenous bolus doses of porcine glucagon of 0.001 −0.05 mg kg−1 caused intense stimulation of the duodenum and jejunum of the dog.
Intravenous infusion of porcine glucagon at 0.025 −0.05 mg kg−1 h−1 caused similar stimulation. In both cases the stimulation was phasic in nature.
Stimulation of the duodenum and jejunum following glucagon was accompanied by a decrease in frequency of the intestinal basic electrical rhythm (BER). No change was seen in the intervals between successive periods of phase III motor activity.
DOI: 10.1111/j.1476-5381.1982.tb09213.x
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