ANTICOAGULANT EFFECTS OF SULPHATED POLYSACCHARIDES IN NORMAL AND ANTITHROMBIN III‐DEFICIENT PLASMAS

Article date: August 1980

By: G. KINDNESS, W.F. LONG, F.B. WILLIAMSON, in Volume 69, Issue 4, pages 675-677

Comparison of the effects of sulphated polysaccharides on thrombin‐induced clotting of normal and antithrombin III‐deficient plasmas suggests the involvement of antithrombin III (AT III) in the anticoagulant activities of cellulose, dextran and xylan sulphates.

AT III appears to play little or no role in the anticoagulant activity of carrageenans.

Comparison of the effects of sulphated polysaccharides on thrombin‐induced clotting of normal and antithrombin III‐deficient plasmas suggests the involvement of antithrombin III (AT III) in the anticoagulant activities of cellulose, dextran and xylan sulphates.

AT III appears to play little or no role in the anticoagulant activity of carrageenans.

DOI: 10.1111/j.1476-5381.1980.tb07921.x

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