Article date: July 1977
By: J.L. IMBS, F. MIESCH, J. SCHWARTZ, J. VELLY, G. LECLERC, A. MANN, C.G. WERMUTH in Volume 60, Issue 3, pages 357-362
1 (t‐Butyl‐amino‐3‐ol‐2‐propyl) oximino‐9 fluorene is a new β2‐adrenoceptor blocking agent with a pA2 of 9.23 ± 0.25 on isolated trachea.
2 It provokes hypertension in normotensive rats and does not prevent arterial hypertension in SHR rats, although it does prevent the renin secretion normally induced by isoprenaline infusion.
DOI: 10.1111/j.1476-5381.1977.tb07508.x
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