The effect of low dose carbidopa/levodopa on prolactin and growth hormone concentrations in patients with breast cancer and in benign breast tumours.

Article date: March 1978

By: MK Jones, ID Ramsay, PG Jenner, in Volume 5, Issue 5, pages 425-430

1 Low doses of carbidopa/levodopa (12.5 mg 1‐alpha‐methyl‐ dopahydrazine, 125 mg levodopa) were administered orally to 29 patients with tumours of the breast (16 with breast cancer, 13 with benign breast disease). 2 Plasma dopa response curves were similar in all the patients studied. 3 Prolactin and growth hormone showed similar responses to carbidopa/levodopa irrespective of age or diagnosis. 4 Prolactin showed an unusual reponse in four patients which has not previously been recorded.

DOI: 10.1111/j.1365-2125.1978.tb01649.x

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