Article date: June 1989
By: LG McAlpine, NC Thomson, in Volume 27, Issue 6, pages 870-872
The angiotensin converting enzyme inhibitors potentiate the wheal response to intradermal bradykinin. Both converting enzyme inhibitors and bradykinin stimulate prostaglandin synthesis and prostaglandins enhance the cutaneous response to bradykinin. We examined the possibility that the increased wheal response to intradermal bradykinin in the presence of enalapril was due to the effect of prostaglandins. Indomethacin did not inhibit the potentiation by enalapril of the wheal response to bradykinin.
DOI: 10.1111/j.1365-2125.1989.tb03452.x
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