Intravenous bumetanide attenuates the rise in plasma vasopressin concentrations during major surgical operations.

Article date: February 1987

By: L Kaufman, PM Bailey, in Volume 23, Issue 2, pages 237-240

During a study in seven patients on the endocrine response to major surgical procedures under general anaesthesia an incidental finding was that the administration of intravenous bumetanide prior to surgical stimulation led to reduced concentrations of plasma vasopressin (AVP) when compared with a control group of patients.

DOI: 10.1111/j.1365-2125.1987.tb03036.x

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