Intra‐hepatic vascular response to sodium nitrite

Article date: March 1969

By: AIDA GEUMEI, I. ISSA, M. MAHFOUZ in Volume 35, Issue 3, pages 456-459

In the perfused liver of the dog, sodium nitrite produced vasoconstriction in the hepatic arterial bed and, particularly, in the portal venous vascular bed.

These effects on the hepatic vasculature may account in part for the reduction of venous return and diminution in cardiac output recorded by other workers, and may therefore be a factor in the clinical efficacy of the nitrites in angina pectoris.

In the perfused liver of the dog, sodium nitrite produced vasoconstriction in the hepatic arterial bed and, particularly, in the portal venous vascular bed.

These effects on the hepatic vasculature may account in part for the reduction of venous return and diminution in cardiac output recorded by other workers, and may therefore be a factor in the clinical efficacy of the nitrites in angina pectoris.

DOI: 10.1111/j.1476-5381.1969.tb08286.x

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