Article date: June 1963
By: B. A. V. PERERA, V. M. ROSENOER in Volume 20, Issue 3, pages 534-539
A commercial preparation of chorionic gonadotropin inhibited gastric acid secretion induced by carbachol in rats. When the preparation was incubated for 10 min at 100° C and pH 7, its gonadotrophic activity, as measured by a simple quantal assay based on the male toad spermiation response, was reduced by 92%. The inhibition of gastric acid secretion by the preparation was not significantly reduced by this treatment. It is concluded that the two activities are separable.
DOI: 10.1111/j.1476-5381.1963.tb01490.x
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