STIMULATION AND SENSITIZATION OF THE ISOLATED VENUS HEART BY CEREBROSPINAL FLUID

Article date: October 1962

By: M. B. BOWERS in Volume 19, Issue 2, pages 295-298

5‐Hydroxytryptamine was not detected in animal cerebrospinal fluid after amine oxidase inhibitors, reserpine, or both. Both human and animal cerebrospinal fluid can produce a stimulating effect on the clam heart which is not due to 5‐hydroxytryptamine. Cerebrospinal fluid also has the property of increasing the sensitivity of the clam heart to 5‐hydroxytryptamine.

DOI: 10.1111/j.1476-5381.1962.tb01191.x

View this article