Article date: February 1962
By: R. K. ARCHER, W. FELDBERG, B. A. KOVACS in Volume 18, Issue 1, pages 101-108
Suspensions of horse eosinophils or the watery extracts of such suspensions were injected intraperitoneally into guinea‐pigs. The eosinophils were obtained from 9 healthy cross‐bred ponies. The number of eosinophils used for each injection varied between 20 and 300 millions. The guinea‐pigs were exposed to a 0.6% histamine aerosol 1 to 8 hr later. The eosinophils of 5 ponies produced protection against the aerosol, the eosinophils of the other 4 ponies did not. Protection when produced did not last as long as 23 hr. The active principle in the watery extracts was stable, after freeze drying, for at least a few weeks.
DOI: 10.1111/j.1476-5381.1962.tb01154.x
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