Article date: December 1960
By: M. N. JINDAL, V. R. DESHPANDE in Volume 15, Issue 4, pages 506-509
Both streptomycin and dihydrostreptomycin in large doses produced neuromuscular blockade in different types of skeletal nerve‐muscle preparations. Streptomycin had a quicker, more marked and a longer‐lasting action than dihydrostreptomycin. Neostigmine reversed a partial block of streptomycin, but a complete neuromuscular block remained unaffected. Calcium ions antagonized the neuromuscular block of streptomycin rapidly but incompletely.
DOI: 10.1111/j.1476-5381.1960.tb00271.x
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