Article date: October 2009
By: Lindsey Tilling, Philip Chowienczyk, Brian Clapp, in Volume 68, Issue 4, pages 484-492
Endothelial progenitor cells are a population of bone marrow‐derived mononuclear cells thought to engage in endothelial repair and hence are considered potential therapeutic agents in many pathological conditions. The mechanism of their exit from the bone marrow to the circulation and damaged tissues, termed mobilization, has not been fully elucidated. Despite this, several pharmacological interventions have been shown to influence mobilization of these specialized cells. Here we review the current understanding of their mobilization.
DOI: 10.1111/j.1365-2125.2009.03486.x
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