Article date: April 1977
By: RS Ehsanullah, P. Turner, in Volume 4, Issue S2, pages 159S-163S
1. The effect of nomifensine on the uptake of 5‐hydroxytryptamine (5‐ HT) and dopamine (DA) into human platelet‐rich plasma has been studied. 2. A significant inhibition of DA uptake was observed at nomifensine 10(‐6) M. 3. 5‐HT uptake was significantly inhibited only at nomifensine 10(‐4) M or more. 4. These results are consistent with those from previous animal experiments and suggest that the human platelet may be used as a model for studying DA uptake as well as that of 5‐HT.
DOI: 10.1111/j.1365-2125.1977.tb05745.x
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