INTERACTION BETWEEN CHOLINEA THEOPHYLLINATE AND SALMEFAMOL IN PATIENTS WITH REVERSIBLE AIRWAYS OBSTRUCTION: Study by the British Thoracic and Tuberculosis Association

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In 54 patients with reversible airways obstruction, a study of the interaction between oral choline theophyllinate (a methyl xanthine derivative) and oral salmefamol (a β₂‐adrenergic receptor stimulant) showed that on peak flow their effect was additive, but failed to demonstrate synergy. The only example of statistically significant synergy was their combined effect on the patients' tremor of the hands.

In 54 patients with reversible airways obstruction, a study of the interaction between oral choline theophyllinate (a methyl xanthine derivative) and oral salmefamol (a β₂‐adrenergic receptor stimulant) showed that on peak flow their effect was additive, but failed to demonstrate synergy. The only example of statistically significant synergy was their combined effect on the patients' tremor of the hands.

DOI: 10.1111/j.1365-2125.1977.tb00430.x

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