Lack of effect of atenolol and nadolol on the metabolism of theophylline.

Article date: February 1990

By: CM Corsi, AN Nafziger, JA Pieper, JS Bertino, in Volume 29, Issue 2, pages 265-268

The effects of 7 days of pretreatment with atenolol, 150 mg day‐1, or nadolol, 80 mg day‐1, on the pharmacokinetics and metabolism of theophylline were determined in six male smokers. Theophylline clearance, volume of distribution, half‐life and the urinary excretion of theophylline and its metabolites were unchanged during either treatment compared with control.

DOI: 10.1111/j.1365-2125.1990.tb03632.x

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