A double‐blind comparison of alprazolam, diazepam and placebo in the treatment of anxious out‐patients.

Article date: February 1985

By: K Davison, RG Farquharson, MC Khan, A Majid, in Volume 19, Issue S1, pages 37S-43S

In a double‐blind 28‐day comparison of alprazolam, diazepam and placebo, alprazolam 1.5‐3 mg/day was of equivalent anxiolytic effect to 15‐30 mg diazepam/day and there was some evidence of antidepressant activity by alprazolam, but not diazepam, in neurotic depression. No serious side‐effects or laboratory abnormalities were encountered.

DOI: 10.1111/j.1365-2125.1985.tb02741.x

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