Article date: July 1982
By: CR Jenkins, CM Chow, BL Fisher, GE Marlin, in Volume 14, Issue 1, pages 113-115
Ipratropium bromide (0.5 mg) and fenoterol (2 mg) produced equivalent peak bronchodilatation between 1 and 2 h after administration to eight patients with chronic partially reversible airways obstruction. The duration of action compared with saline was 6 h for ipratropium and 4 h for fenoterol. Both drugs in combination produced greater bronchodilatation than either drug alone. The increase in FVC was disproportionately greater than FEV1 with both drugs and saline, suggesting relief of obstruction of small airways.
DOI: 10.1111/j.1365-2125.1982.tb04946.x
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