Article date: April 1980
By: V Ventafridda, C Fochi, D Conno, E Sganzerla, in Volume 10, Issue S2, pages 343S-346S
1 Prostaglandins may precipitate or exacerbate pain and they may be produced by several tumours. 2 Non‐steroidal anti‐inflammatory drugs (NSAIDs) inhibit prostaglandin synthesis and may also inhibit bone metastases and enhance immune responses. 3 NSAIDs alone or in association with narcotics or psychotropics may not only afford the best pain relief in neoplastic disease, but also modify the progress of the tumour. 4 The effect of NSAIDs on the gastrointestinal tract is generally adverse.
DOI: 10.1111/j.1365-2125.1980.tb01820.x
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