Principles for inclusive implementation of the undergraduate pharmacology core curriculum
Through our vision for inclusive pharmacology, the Society commits to placing equity, diversity and inclusion at the heart of pharmacology, whether in terms of the opportunity for a successful career, or in benefitting from pharmacology research. How pharmacology is taught, and to whom, is at the heart of achieving this. Therefore, we have developed the following principles for inclusive implementation of the undergraduate pharmacology curriculum as part of a holistic review to help ensure that the curriculum continues to meet the needs of students, responds to an evolving discipline - and ultimately reflects the real-world settings that require pharmacology education and training.
These principles were developed by an expert steering group and capture the cross-cutting theses that emerged from a wider review of the Society's undergraduate core curriculum. We hope that using them will support the development and delivery of pharmacology programmes that:
- Positively impact research and health across global communities
- Acknowledge cultural and historical influences on the discipline
- Value the individuality of all who benefit from and contribute to pharmacology
- Operate within inclusive educational environments, including collaboration & setting expectations with students
- Inspire knowledge sharing and discussion within and between educator and student communities
The Society acknowledges that progress in inclusive pharmacology education will emerge as part of a reflective, collaborative and community-driven approach. These principles are intended to spark discussion and to help continue to build such a community. We know that there will be gaps in knowledge or confidence, and welcome discussion about the use of language. We believe that being honest and curious about where we are now as a collective will help the focus of progressive discussions and support shared learning. To this end, the Society has named inclusive pharmacology as a priority education area, committing funding and staff time to support the development and dissemination of resources, good practice and continued learning. This will be an evolving process, and our intention is to progress it in partnership with the global pharmacology community.
The Society thanks the International Union of Basic & Clinical Pharmacology (IUPHAR) for endorsing these principles.
Principles to enable inclusive delivery
Pharmacokinetics and pharmacodynamics
- Explore genetic and epigenetic influences on drug action and how these lead to interindividual differences in response to drugs
- Consider how drug effects can be significantly impacted by dietary and environmental variation
- Consider how drug effects can be significantly impacted by physiological variables such as age, sex and pregnancy
Pharmacological research
- Examine the need for research to include a diverse and representative pool of subjects
- Consider drugs in a variety of contexts e.g. as the focal point of clinical trials, as active ingredients in medicines/remedies, as positive controls, as tools in mechanistic studies
The global pharmacology community
- Provide examples of drugs to treat a broader range of diseases from across the world
- Recognise global inequalities (e.g. health inequlities, data gaps) and the impact of dominant power structures (e.g. patriarchy, colonialism, capitalism) and biases in generating and perpetuating them
- Explore the historical and geographical origins of drugs and therapeutic interventions, and recognise contributions to our understanding from all individuals, environments and cultures
- Acknowledge regional variations in local rules, regulations, resources, technology and approaches to the discovery, development and administration of drugs
Accessible pharmacology
- Ensure learning environments and materials are fully accessible by accounting for differences in educational skills, backgrounds and learning needs, taking care not to assume expertise or cultural norms
- Provide support and additional opportunities for learning in critical areas, particularly mathematics, where considerable variation in educational background is recognised
- Minimise the use of extraneous technology or software where possible, or provide alternative means to access them
Use of language explanatory notes
We have chosen to include some explanatory notes alongside these principles regarding our use of language. Language is meaningful and can be subject to interpretation. Our intention is to be explicit about our choice of language, and how we hope it will support inclusive implementation - and to invite comment and update as we learn
a. Inclusive pharmacology: The Society acknowledges that the term 'inclusive' has been used in some education settings to solely mean 'accessible'. Our intention is that these principles capture accessibility - but we use the word 'inclusive' here as an umbrella term in its broadest sense. We recognise that as written, the curriculum hides biases and assumptions that reflect the impact of dominant power structures (e.g. patriarchy, colonialism, capitalism) that must be named if they are not to be perpetuated through implementation. For example, the curriculum is Euro-centric - it is currently framed through a Western lens, valuing Western approaches to drug discovery and development, to terminology, and to Western educational norms. It also hides divides (e.g. between Global North and Global South) and other biases and assumptions prevalent in research, development and health care, such as data gaps that perpetuate health inequalities. Naming inclusivity as a priority for implementation is intended to help acknowledge and redress such biases.
b. Drug: We recognise that across different cultures and geographical regions, the term 'drug' has a variety of meanings and connotations often referring to Western therapeutic approaches or even abuse of illicit substances. In our documentation, the term 'drug' refers to a chemical or biological entity that induces physiological changes as a result of interactions with a target within the organism, The term is intended as a catch-all for entities that might be active ingredients e.g. within experimental tools, prescribed medicines, plant or herbal preparations, natural products or traditional remedies. In clarifying this, it is hoped that we can open up the pharmacology curriculum to recognise diverse cultural contributions to therapeutic approaches and practice.
c. Genetic and epigenetic influences: We talk about inter-individual genetic variation in the context of contribution to scientific and clinically meaningful difference in drug responses. We have chosen not to use the term 'ethnicity' in the context of genetics because there are more similarities than differences between ethnic groups. Relying on ethnicity as a proxy for genetics is problematic and risks perpetuating genetic determinism, the tendency for people to ascribe differences in behaviours or traits to genetics alone. To understand differences in individual drug responses, researchers should directly measure the presence of implicated alleles alongside other factors, such as diet, age and sex.
Core Knowledge Statements
Having successfully completed an undergraduate degree in Pharmacology, graduates have knowledge and understanding of the below Core Knowledge Statements. We have also included the broad learning outcomes and some resources.
Theoretical principles of drug action
Drugs can be used in health and disease, giving examples from body systems
Broad learning outcome:
- Describe the mechanism of action, clinically relevant pharmacokinetics and major adverse side effects of drugs that are commonly used in therapeutic strategies, giving examples from the body systems for example statins and beta blockers
Resources:
How drugs interact with their targets, including drug-receptor theory
Broad learning outcome:
- Describe the molecular targets for drug action within the body including receptors, ion channels, enzymes and transporters, and outline the principles of how drugs interact with their targets.
Resources:
Pharmacodynamics (molecule to whole organism)
Broad learning outcome:
- Explain drug and chemical post-target effects on cellular signalling and how these integrate into responses. Describe how pharmacological concepts (e.g. Emax, EC50, Kd, receptor occupancy), along with the mechanisms of action relate to dosing regime and whole organism effect.
Resources:
- https://www.cellsignal.co.uk/pathways/by-research-area
- Speed pharmacology YouTube channel: https://www.youtube.com/channel/UC-i2EBYXH6-GAglvuDIaufQ/videos?view=0
How physiological and pathophysiological processes are affected by drug action
Broad learning outcome: Describe the ways in which drugs interacting with their targets influence specific downstream events that lead to changes in cell, tissue, organ and / or whole organism performance, explaining the relevance of this in health and disease
Resources:
- Drugs matched to diseases: https://www.youtube.com/watch?v=FD6nkFz1HK8
- Rang and Dale’s Flash Cards: https://www.elsevier.com/books/rang-and-dales-pharmacology-flash-cards/mckenzie/978-0-7020-7905-4
- Lots of examples on YouTube of videos and lectures around diseases and the drugs used to treat them
Pharmacogenomics
Broad learning outcome: Explain (with examples) how individual and population genetics can influence pharmacokinetic and pharmacodynamic responses to drugs, relating this to personalised medicine and drug discovery.
Resources:
- Case study: https://tidsskriftet.no/en/2008/08/case-reports/60-year-old-man-heart-failure-dry-cough-and-elevated-inr-values
- PEP: https://www.pharmacologyeducation.org/clinical-pharmacology/individual-variation-drug-response
- FDA: https://www.fda.gov/medical-devices/precision-medicine/table-pharmacogenetic-associations
- Tulane: https://tmedweb.tulane.edu/pharmwiki/doku.php/basic_principles
Principles of toxicology and their application in safety pharmacology
Broad learning outcome: Describe the relationship between dose, exposure and adverse effects of a substance, relating this to its safe and effective use in an organism
Resources:
- Pharmaceutical Toxicology by Mulder, G J & Lennart,D (2006) Pharmaceutical Press. ISBN 0-85369-593-8
Principles of translational research and experimental medicine
Broad learning outcome: Describe translational research and describe the stages from foundational and pre-clinical research through to application of new therapies and diagnostics in individuals and populations
Resources:
Methodological principles
Qualitative and quantitative statistical tools and analytical methods used to interpret pharmacological data
Broad learning outcome: Apply knowledge of maths and statistics to summarise and visualise data, using appropriate models and inferential tests to interpret results and make inferences in relation to the study design.
Resources:
- https://www.statstutor.ac.uk/
- https://www.graphpad.com/guides/prism/latest/statistics/index.htm
- https://statistics.laerd.com/
- https://cran.r-project.org/web/packages/drc/drc.pdf (dose response curve package for use with R Studio)
The scientific method (hypothesis formulation, hypothesis testing, experimental design, experimental analysis).
Broad learning outcome: Use the research literature to identify an appropriate research question and develop a testable hypothesis to answer it. Design a suitable series of experiments to test a hypothesis and understand principles of good experimental design. Critically appraise the design and analysis of an experiment to test a hypothesis.
Resources:
Appropriate and emerging methods for interrogating the pharmacodynamic effects of drugs
Broad learning outcome: Explore different methods for interrogating the pharmacodynamic effects of drugs, for example, fluorescent techniques or molecular dynamics approaches. Explain which methods are appropriate for measurement of different parameters
Resources:
- General considerations around PD and measurement in preclinical trials:
- What is Pharmacodynamics? (news-medical.net)
- Case study determining pre-clinical PD of cariprazine
- Preclinical pharmacodynamic and pharmacokinetic characterization of th | DDDT (dovepress.com)
- Examples of emerging strategies and their use in PD measurement:
- Pharmacodynamic assays to facilitate preclinical and clinical development of pre‐mRNA splicing modulatory drug candidates - Shi - 2015 - Pharmacology Research & Perspectives - Wiley Online Library
Appropriate and emerging methods for interrogating the pharmacokinetic effects of drugs
Broad learning outcome: Explore different methods for interrogating the pharmacokinetic effects of drugs, for example, labeling or mass spectroscopy of plasma or urine samples. Explain that total plasma or tissue concentrations can be predicted by incorporating key pharmacokinetic parameters into mathematical models.
There are three broad areas within in:
- measuring drug concentrations
- using drug concentrations to predict dose regimens using models
- the relationship (or lack of) with drug action
Resources:
- Therapeutic drug monitoring: https://www.nps.org.au/australian-prescriber/articles/therapeutic-drug-monitoring
- Rowland, M. and Tozer, T. N.2011. Clinical Pharmacokinetics and Pharmacodynamics: concepts and applications. Fourth Ed.
- D J Birkett, 2010 Pharmacokinetics Made Easy, 2nd Ed, McGraw-Hill
- A.A. Heller, S.Y. Lockwood, T.M. Janes, and D.M. Spence (2018) Technologies for Measuring Pharmacokinetic Profiles, Annual Review of Analytical Chemistry, Vol. 11:79-100 https://doi-org/10.1146/annurev-anchem-061417-125611
- Drug absorption: https://www.pharmacologyeducation.org/pharmacology/drug-absorption
- Drug distribution: https://www.pharmacologyeducation.org/pharmacology/drug-distribution
- Drug metabolism: https://www.pharmacologyeducation.org/pharmacology/drug-metabolism
- Drug excretion: https://www.pharmacologyeducation.org/pharmacology/drug-excretion
- Clinical pharmacokinetics: https://www.pharmacologyeducation.org/clinical-pharmacology/clinical-pharmacokinetics
- Interindividual variability in pharmacokinetics: https://www.pharmacologyeducation.org/clinical-pharmacology/individual-variation-drug-response
- Therapeutic drug monitoring: https://www.pharmacologyeducation.org/clinical-pharmacology/therapeutic-drug-monitoring
- Drug interactions: https://www.pharmacologyeducation.org/clinical-pharmacology/drug-interactions
Drugs as pharmacological tools in scientific research
Broad learning outcome: Explore the use of drugs as tools for scientific research and evaluate the impact of these on the scientific knowledge gained using specific examples
Resources
- Strathclyde Pharmacology Simulation: http://spider.science.strath.ac.uk/sipbs/software_sims.htm
- SWIRL MIDBIT practical (link in development) (contact education@bps.ac.uk if interested)
- Various exercises on Learning Science: https://learningscience.co.uk/labsims
- The principles of reduction, refinement and replacement in the use of animals in research
The principles of reduction, refinement and replacement in the use of animals in research
Broad learning outcome: Explain the use of animals in research with accurate reference to the 3 Rs and their use in practice
Resources
Drug discovery & development
The multidisciplinary nature of drug discovery and development and the pivotal role played by pharmacology
Broad learning outcome: Describe the role of multiple disciplines in drug discovery and development e.g. chemistry, physiology, pathology. Describe how the integration of knowledge from these disciplines with pharmacology is critical for the drug discovery and development process.
Resources:
- Drug Design and Development by Rostron, C. (2020) Oxford University Press. ISBN 978-0-19-874931-8
The stages of drug discovery and development
Broad learning outcome: Describe the stages of drug discovery and development including the purpose, importance, design and limitations of each stage
Resources:
Principles of clinical trial design
Broad learning outcome: Describe the key principles underpinning the design of a clinical trial for a new therapeutic entity.
Resources:
How knowledge of pathophysiology can yield insights into drug targets and new therapeutic avenues
Broad learning outcome: Identify suitable targets for possible pharmacological intervention by understanding the mechanisms underlying the pathophysiology of a disease and limitations of current therapies. Explain how knowledge of disease mechanisms lead to the development of named drugs (rational drug design).
Resources:
- Story of James Black’s work on beta blockers
- Story of ACE inhibitor development based on envenomation by Brazilian pit viper
- Roche video summary of how they identify novel targets https://www.roche.com/research_and_development/drawn_to_science/target_identification.htm
Emerging therapeutic avenues
Broad learning outcome: Describe emerging therapeutic avenues for example biologics, nanotechnology, cell and gene therapy, immunological therapies and other medicine modalities.
Resources:
- Excemed Home: Resources | EXCEMED
- Multiple Sclerosis emerging therapeutic strategies talk: Emerging therapeutic strategies | EXCEMED
The use of gene modification techniques in drug discovery and development
Broad learning outcome: Explain the fundamentals of why different gene modification techniques are used to modify receptors or proteins within the drug discovery process using examples such as fluorescent/bioluminescent tags, genomic modification with siRNA or CRISPR, and tagged receptors in vivo.
Resources:
- Addgene GFP guide: https://blog.addgene.org/plasmids-101-green-fluorescent-protein-gfp
- siRNA https://horizondiscovery.com/en/applications/rnai/sirna-applications
- CRISPR Guide: https://www.addgene.org/guides/crispr/
- Nature CRISPR transforming drug discovery: https://www.nature.com/articles/d41586-018-02477-1
- Tissue specific KO models https://www.genoway.com/services/customized-mouse/knockout-models/conditional-ko-tissue.htm
Commercial drug discovery techniques
Broad learning outcome: Describe the key techniques used in successful industrial drug discovery, from target selection, hit discovery, PK/PD and toxicology to commercial impact.
Resources:
Regulatory processes to include medicine quality, safety and effectiveness
Broad learning outcome: Explain the purpose and importance of the international medicines regulatory process and list the requirements for making an application to a regulatory body.
Resources:
The challenges associated with developing and assessing the efficacy and safety of new therapeutic approaches
Broad learning outcome: Describe the challenges associated with developing and assessing the efficacy and safety of new therapeutic approaches, including the testing strategies and legal requirements involved
Resources:
- Drug Discovery and Development, Third Edition O'Donnell et al: (2021). CRC Press ISBN 978-1-138-08026-3
The societal impact of the discipline
The ethical principles of research, including clinical trials and animal research (design, implementation and reporting)
Broad learning outcome: Discuss the ethical issues surrounding scientific and medical research including the use of animals, principles of Humane Experimental Technique (3Rs) and the involvement of human participants in clinical trials, describing the associated legal and regulatory requirements.
Resources:
- Animal ethics: Lewis DI (2009) Animal Welfare, Ethics and the 3Rs: Training materials and resources. Available at: http://www.lasa.co.uk/PDF/3Rsresourcee-versionDec09s.pdf
- Bioethics: John A. Bryant, Linda Baggott la Velle (2018) Introduction to Bioethics, 2nd Edition ISBN: 978-1-118-71959-6
- Clinical trials: Cecilia Nardini (2014) The ethics of clinical trials Ecancermedicalscience 8: 387. doi: 10.3332/ecancer.2014.387
How pharmacology relates to social challenges and public health
Broad learning outcome: Examine how pharmacology can inform and advance understanding of social challenges and public health issues, for example risk/benefit analysis of drugs, social determinants of disease (progression, outcomes and response to treatment), and policy related to public health.
Resources:
- BPS resources on drugs in sport e.g. steroid use in adolescents, doping, reform of doping rules Resources inculde YouTube video (577) Maintaining a healthy body – advice from an Olympic champion - YouTube and multiple articles in BJP/BJCP
- Involvement of pharmacologists in addiction and policy in drugs of abuse e.g. opioid dependence, alcohol dependence, examples include David Nutt on use of psychedelic drugs for therapy and relative risk of drugs of abuse (and also how the law can hamper research). The Challenge of novel psychoactive substances (577) Dr James Dear: The challenge of novel pyschoactive substances - YouTube. Use of pharmacology to develop CBD and other cannabinoid drug candidates from cannabis separating the social and medical use of drugs of abuse/recreational drugs and leading to changes in the law.
- Covid-19 response – vaccination programmes other endemics/pandemics such as HIV
- Using pharmacology to inform/debunk/refine nutritional claims (omega-3/antioxidants/polyphenolic compounds)
- Women in clinical trials/choice in breast feeding (577) The change in mindset that is needed when talking about women in research - Dr Catriona Waitt - YouTube
- (577) How research can support freedom of choice regarding breastfeeding - Dr Catriona Waitt - YouTube
- Sex as a biological variable (577) Sex as an experimental variable: creation of a policy for the British Journal of Pharmacology - YouTube
- Could explore examples such as the impact of culture on medication and alternative medicine use. Social determinants of disease e.g. COPD (caused by smoking and pollution) and pain perception (influenced by mental wellbeing which is linked to social factors).
- Exploring the role of pharmacology in addressing unmet health needs
The impact of pharmacology on patient care with respect to the safe and effective use of medicines
Broad learning outcome: Appraise the importance of pharmacology in the discovery and development of drugs used to prevent and treat disease, and the impact of clinical pharmacologists on patient care with respect to ensuring the safe and effective use of medications.
Resources:
The various career paths and opportunities afforded by a pharmacology degree
Broad Learning Outcome: Identify the various career paths and professional opportunities afforded by a pharmacology degree including academic, industrial and clinical opportunities
Resources:
Core Skills Statements
Having successfully completed an undergraduate degree in Pharmacology, graduates will be able to demonstrate competence in the below Core Skills Statements. We have also provided some suggestion assessments and resources beneath each skill.
Experimental techniques
Be able to formulate a scientific hypothesis
Assessment:
- Provide a redacted research article and get students to piece together the information provided to suggest a testable hypothesis.
- Present a scientific problem and its context and get students to design and present a hypothesis explaining ways in which it might be tested.
- Assess student abilities to write, explore and explain a scientific hypothesis within a research project
- Participation in group exercises where students are provided with information about a scientific problem and question and have to determine a hypothesis to explore it
Resources:
- Lab exercise: https://journals.physiology.org/doi/full/10.1152/advan.00002.2001
- Hypothesis development exercise example: Hypothesis development and experimental approaches
- Any research article with hypothesis and aims etc redacted to provide context for experimental investigation - BJP articles seem particularly relevant to this.
Implement principles of good experimental planning and design.
Assessments:
- Preparation of mock grant proposals based on preliminary data from research groups
- Participation in workshop/journal club focusing on the design of the experiments presented within a published study. Including analysis of whether conclusions match the data, additional experiments needed and validity of conclusions
- Construction of an experimental plan including timeline
- Critique of pharmacology research articles to assess whether studies meet the principles of good experimental design
- Reflection on experimental design following attendance at a research presentation
Resources:
- Communicating Research Intent and Value in NIH Applications: Plain Language Examples
- NC3Rs research design tool - The Experimental Design Assistant - EDA | NC3Rs (components of experiment can be added in and see if their idea is appropriate) - currently more research focused so could be used as a worked example.
- Blinding eResource Blinding eLearning resource | British Pharmacological Society (bps.ac.uk)
- Experimental proforma or similar to allow students to see experimental design
- Mathematics/statistical perspectives to determine experimental design n numbers etc. Recognising the correct stats being done etc. what would have been better?
Identify the most appropriate statistical approach.
Assessments:
- Provide simulated data and ask students to do an appropriate statistical analysis
- Provide data for example from a drug trial in wildtype and knock out animals. Assess student's ability to identify the statistical approach, apply this and present the data graphically
Resources:
- GraphPadPrism help pages - Support - GraphPad
- Cambridge university bioinformatics summer school - Training - Cancer Research UK Cambridge Institute
- SPSS online tutorials e.g. SPSS Beginners Tutorials (spss-tutorials.com) (many others available)
Be able to make appropriate decisions about methodology when designing a study
Assessments:
- Assess methodological approaches in student grant and project proposals
- Participation in a groupwork exercise where students identify a drug to repurpose, and design a study with appropriate controls and data analysis
- Critique of real/hypothetical research studies to identify issues in methodology and experimental design
Resources:
- Experimental design resource NC3Rs Experimental design and reporting | NC3Rs
- ARRIVE guidelines The ARRIVE guidelines 2.0 | ARRIVE Guidelines
- Recovery study - Welcome — RECOVERY Trial
- Covax database - COVAX (who.int)
Be precise and accurate when performing core laboratory skills
Assessments:
- Completion of a laboratory task with a quantifiable output e.g. determining an unknown concentration from a standard curve
- Observation of students completing and discussing laboratory tasks
- Completion of a series of OSPE stations assessing various aspects of laboratory work
Resources:
- OSPE style assessments BMSForum19_P1_DerekScott (ed.ac.uk)
- Determination of unknown concentrations (e.g. protein assays, methylene blue) e.g. 1.8: Serial Dilutions and Standard Curve - Biology LibreTexts
Carry out experiments with awareness of Good Laboratory Practice (GLP)
Assessment:
- Assess laboratory skills in a wet-lab practical write up / laboratory notebook recording.
- Assess students’ ability to annotate/appropriately identify examples of good and poor practice from examples of laboratory work
Resources:
Be able to use quantitative methods to collect, process and present data
Assessment:
- Participation in a workshop where students analyse data then present it using a traditional lab report, poster or oral presentation
- Completion of capstone project in the final year
- Writing of a research proposal including for example, research problem, proposed methodology and data analysis
Resources:
- Molecular Pharmacology January 1, 2020, 97 (1) 49-60; DOI: https://molpharm.aspetjournals.org/content/97/1/49
- History of Quantitative Methods in Pharmacology: https://doi.org/10.1038/sj.clpt.6100248
- Selected quantitative study examples: Quantitative Pharmacology - an overview | ScienceDirect Topics
Be able to use in vitro techniques in pharmacology
Assessment:
- Assess lab practical reports which use in vitro techniques
- Student participation in data analysis workshops on in vitro techniques
- Orak presentations/Q&A sessions to test students' knowledge and understanding of in vitro techniques
Resources:
- In vitro models article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1751497/
- In vitro alternatives to animal models: https://pubs.rsc.org/en/content/articlehtml/2015/tx/c5tx00123d
- ADInstruments esources: https://www.adinstruments.com/research/in-vitro/pharmacology-isolated-tissue-and-organs
- In vitro model simulations: University of Strathclyde
Have the necessary theoretical and/or practical training to be able to use in vivo techniques in pharmacology
Assessment:
- Student participation in scenario / experimental technique workshops
- Student completion of the NC3Rs Experimental Design Tool training and assessment
- Objective structured practical examination (OSPE) to assess legal, ethical and practical elements of in vivo techniques in pharmacology
- Students select and explore a disease, then present an appropriate in vivo model to study the disease, e.g. using Jackson Lab - knockout animal database
- Critique a project licence application
Resources:
- NC3Rs Experimental Design Tool: The Experimental Design Assistant - EDA | NC3Rs
- Jackson Lab Knockout Mouse Database:Knockout Mouse Project (KOMP) (jax.org)
- ADINstruments Lt: Lt | Online Physiology Software & Life Science Lessons | ADI (adinstruments.com)
- HO PIL course material https://www.gov.uk/guidance/research-and-testing-using-animals
- JOVE to help design assessment resources https://www.jove.com/
- SYCRLE:https://www.radboudumc.nl/en/research/departments/health-evidence/systematic-review-center-for-laboratory-animal-experimentation
Data handling and analysis
Identify and use information from appropriate and reliable sources
Assessment:
- Participation in workshops where students are given experimental questions to answer, then must find resources as a group, discuss the information, then present with Q&As
- Assess understanding of appropriate resources to use in the writing of a scientific article (primary research papers; peer-reviewed websites; science versus lay websites/blogs)
- Create an infographic integrating information from appropriate and reliable sources
Resources:
- Open University guide to finding credible resources: Finding resources for your assignment | Library Services | Open University
- Nature guide to research articles: https://www.nature.com/scitable/topicpage/scientific-papers-13815490/
- Local University Library Guides: e.g. finditfastlibraryworkshops [licensed for non-commercial use only] / Home (pbworks.com)
Integrate information from a range of sources and critically evaluate it
Assessment:
- Assess student ability to critically evaluate published work on a given topic in a journal club
- Assess students written work (e.g. dissertation) which critically appraises literature
- Provide students with information about chemical compounds and associated data and ask them to evaluate their potential as therapeutic agents
Resource:
- FDA resources https://www.fda.gov/
Students to search BJP and other journals for content resources https://bpspubs.onlinelibrary.wiley.com/journal/14765381
Apply and interpret appropriate statistical tests correctly
Assessment:
- Assess student analysis of final year project data
- Provide students with a range of published papers and assess their ability to critically evaluate the statistical approaches used
Resource:
- Published papers: https://bpspubs.onlinelibrary.wiley.com/journal/14765381
- NC3Rs experimental design resources https://nc3rs.org.uk/overview-resources-experimental-design-hub
- in vivo stat package for analysis https://invivostat.co.uk/
- David Colquhoun- webpages http://www.dcscience.net/
Use a common statistical software package
Assessment:
- Computer-based exercises where students are provided with a specific statistical software package and have to analyse given data
- Assess student preparation of laboratory reports where data is presented and analysed using a defined statistical software package
- Preparation of a dissertation with data analysed using one or more statistical software packages.
Resource:
Pros and cons plus help guides for different statistical packages
- SPSS https://www.ibm.com/products/spss-statistics (30 days free)
- Minitab https://www.minitab.com/en-us/products/minitab/free-trial/ (30 days free trial)
- GraphPad Prism https://www.graphpad.com/scientific-software/prism/ (30 days free trial)
- David Colquhoun- webpages http://www.dcscience.net/
- Citing and referencing YouTube video: https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&ved=2ahUKEwih1rThyNf0AhVNZMAKHeP3Be0QwqsBegQIIBAB&url=https%3A%2F%2Fwww.youtube.com%2Fwatch%3Fv%3DU3ntLOPqCpg&usg=AOvVaw2XtQ_nMv1WnWLW6oI1QA8c
- Any citing and referencing manager help / how to use section e.g. write n cite, refworks, mendeley etc
Accurately record and reference source material
Assessment:
- Assessment of any written piece of work (e.g. dissertation) that requires cited references
- Student participation in workshops around citing and referencing appropriately
- Preparation of “mock” manuscripts for certain publications strictly adhering to authors guidelines
- Provide students with examples of poorly cited work and get them to identify the errors
Resource:
- Local University library guides to citing and referencing: e.g. Referencing and RefWorks | Library, Special Collections and Museums | The University of Aberdeen (abdn.ac.uk)
- Citing and referencing YouTube video: https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&ved=2ahUKEwih1rThyNf0AhVNZMAKHeP3Be0QwqsBegQIIBAB&url=https%3A%2F%2Fwww.youtube.com%2Fwatch%3Fv%3DU3ntLOPqCpg&usg=AOvVaw2XtQ_nMv1WnWLW6oI1QA8c
- Any citing and referencing manager help / how to use section e.g. write n cite, refworks, mendeley etc
Analyse and interrogate large data sets
Assessment:
- Assess a journal club presentation that requires understanding of big data for example a Cochrane review
- Student participation in an assessed workshop where large data sets are analysed
- Provide a figure to students and ask them to analyse and write a figure legend
Resource:
Working practices
Keep up to date with relevant literature and developments in pharmacology
Assessment:
- Assess student contributions to a blog/discussion board of “breaking news” style short articles
- Student creation of an e-portfolio of new findings and techniques gained throughout the year for presentation and discussion
- Student participation in a journal club presentation of a recent research paper
Resource:
- Students to access BJP and other suggested journals list compiled; Science/New Scientist/Nature/PNAS
- BLOG examples:
- https://www.sciencedaily.com/news/health_medicine/pharmacology/; https://www.news-medical.net/condition/Pharmacology; https://www.nature.com/subjects/pharmacology
- Eduflow: Eduflow · An easier, more powerful LMS
- PeerMark: About PeerMark™ assignments (turnitin.com)
- Discussion board weekly tweet task
Perform research efficiently through good planning and management
Assessment:
- Assess student literature reviews
- Assess student experimental design plans for projects
- Students develop research proposals / mock grant applications
- Students demonstrate use of GANNT charts for projects / research strategies
Resource:
- (Mis)informed about what? What it means to be a science-literate citizen in a digital world
- Writing a good research plan: Writing a Research Plan | Science | AAAS
- Printable guide to planning research: a-printable-step-by-step-guide-to-planning-your-research-project.pdf (plymouth.ac.uk)
- If animal experiments -NC3Rs experimental design tool: The Experimental Design Assistant - EDA | NC3Rs
- Grant writing exercises / ideas: Grant Proposals (or Give me the money!) – The Writing Center • University of North Carolina at Chapel Hill (unc.edu)
Organise and accurately record information, for example, in a laboratory book
Assessment:
- Assess student preparation of a formal laboratory report
- Student completion of best practice laboratory record templates
- Assess student record keeping during practicals and projects using a laboratory notebook and discussing the importance of this as a competency exercise
- Students complete and record a practical exercise at beginning of year and are assessed repeating the exercise at the end of the year supported only by their notes.
Resource:
- Laboratory report guidelines: Writing a Science lab report - Research & Learning Online (monash.edu)
- Laboratory notebook record keeping: How to Write Lab Notes and Lab Reports (scienceinteractive.com)
- Writing a laboratory notebook: Guidelines for keeping a laboratory notebook (rice.edu)
- Writing and using a laboratory notebook for assessment: Laboratory notebooks and reports (warwick.ac.uk)
- Keeping a laboratory notebook: University of Glasgow Lab Notebook Guidance.docx (live.com)
- NIH Laboratory notebook webinar: Lab_Notebook_508_(new).pdf (nih.gov)
Work independently
Assessment:
Many examples of assessments of individual work throughout the programme years. These include assessment of:
- independent work in the laboratory to set up tissue, dilute drugs, generate standard curve.
- preparation of scientific essays, laboratory reports, final year projects and literature reviews.
Resource:
Any academic task involving independent work supports assessment here. Some examples:
Work constructively in small groups or teams
Assessment:
- Completion of group work to investigate repurposed drugs relating to a condition
- Preparation of a patient information leaflet as part of a group
- Participation in team based learning with in depth peer assessment
- Development of a website about a specific pharmacology area as part of a group
- Assessing experimental design approaches in groups / teams
Resource:
Any group based activity would work here. Some examples include:
Team based learning: https://bmcmededuc.biomedcentral.com/articles/10.1186/s12909-020-02287-y
Communicate effectively to scientific and non-scientific audiences (including written and oral forms)
Assessment:
- Completion of a drug design task where patient information leaflet created (for non-scientific audience) and new drug is designed and presented (scientific audience)
- Creation of posters for scientific or non-scientific audiences
- Delivery of seminar presentations to scientific audience
- Delivery of a research talk to a non-scientific audience
- Preparation of a research project thesis and presentation to scientific and public audiences
Resource:
- 3D project individual and group task
- Research project poster guidelines (adaptable between scientific or non-scientific audiences)
- Group poster project - Medical challenges (adaptable between scientific or non-scientific audiences)
- Research project thesis
- Communicating science to a non-science audience: Tips for communicating your scientific research to non-experts (scientifica.uk.com)
- Tips for communicating science to non-experts: 9 Tips For Communicating Science To People Who Are Not Scientists (forbes.com)
- Science Outreach Ideas List: Science Outreach Ideas — The Running List – Scivic
Core Attitudes Statements
The Society’s Education and Training Committee supports educators in delivering the Core Curriculum by providing practical tools and resources. Consequently, we have:
- Developed broad learning outcomes for each Core Curriculum Knowledge Statements
- Identified assessment examples which align well with each Core Curriculum Skills Statement
- Linked to relevant resources against each statement to help deliver them
For the Core Curriculum Attitude Statements, we have created a downloadable, editable proforma. This acts as a portfolio for students to record and reflect on their learning, either independently or with lecturers, towards the end of their degree. It includes suggested activities such as final year projects, placements, outreach, conferences, research, and lab practicals.
Completing the proforma allows students to evidence their professional attitudes, such as responsibility, awareness, and inclusive working practices – linking directly to employability. Educators can also use it to map how programmes or activities foster these attitudes, while students can reflect on their personal development and use the portfolio to strengthen applications for jobs, placements, or further study.
Core Attitudes Statements Example
| No. | Having successfully completed an undergraduate degree in Pharmacology, graduates will have: | Achieved? (Y/N) | What tasks have been completed that evidence the attitudes listed? |
|---|---|---|---|
| 1 | A concern for detail and quality |
| |
| 2 | A curious attitude and openness when interpreting data |
| |
| 3 | A confident and adaptable working attitude |
| |
| 4 | A willingness to accept a challenge |
| |
| 5 | The courage to stand up for their principles under pressure |
| |
| 6 | A resilient attitude in the face of failure or unexpected outcomes |
| |
| 7 | The ability to work to the highest principles of scientific integrity, following ethical working practices |
| |
| 8 | The ability to apply creative/innovative approaches to addressing complex problems |
Completion of research projects | |
| 9 | The ability to maintain effective working relationships and collaborations |
| |
| 10 | The ability to work to fixed deadlines and manage pressure |
| |
| 11 | A willingness to engage with developments across science and healthcare |
| |
| 12 | The ability to identify employment opportunities and independently pursue personal career goals |
| |
| 13 | The confidence and ability to apply their skills in a real-world setting |
| |
| 14 | The skills for lifelong learning e.g., independence, time management, organisation and planning, initiative, knowledge transfer |
| |
| 15 | An appreciation of the societal relevance and impact of pharmacology |
| |
| 16 | An appreciation of the value of public engagement and outreach |
| |
| 17 | The ability to self-assess performance |
| |
| 18 | An understanding of how to evaluate risk |
|
Download as a PDF
Download the Undergraduate Core Curriculum and Principles for Inclusive Delivery as a PDF
The Society’s Education and Training committee are keen to ensure that the undergraduate curriculum stays relevant and up to date in between more formal reviews.
We welcome all feedback. If you would like to send us some feedback, please email education@bps.ac.uk.