Pharmacology Research & Perspectives

Synergistic interaction between the agonism of cebranopadol at nociceptin/orphanin FQ and classical opioid receptors in the rat spinal nerve ligation model

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Article date: December 2018

Authors: Thomas Christoph, Robert Raffa, Jean De Vry, Wolfgang Schröder

Dual androgen receptor (AR) and STAT3 inhibition by a compound targeting the AR amino‐terminal domain

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Article date: December 2018

Authors: Yaping Hua, Waqas Azeem, Yunheng Shen, Shoude Zhang, Jan R. Olsen, Anne M. Øyan, Xisong Ke, Weidong Zhang, Karl‐Henning Kalland

Pharmacological profile of the neuropeptide S receptor: Dynamic mass redistribution studies

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Article date: December 2018

Authors: Chiara Ruzza, Federica Ferrari, Remo Guerrini, Erika Marzola, Delia Preti, Rainer K. Reinscheid, Girolamo Calo

Onset timing of statin‐induced musculoskeletal adverse events and concomitant drug‐associated shift in onset timing of MAEs

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Article date: December 2018

Authors: Hayato Akimoto, Akio Negishi, Shinji Oshima, Mitsuyoshi Okita, Sachihiko Numajiri, Naoko Inoue, Shigeru Ohshima, Daisuke Kobayashi

Risdiplam distributes and increases SMN protein in both the central nervous system and peripheral organs

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Article date: December 2018

Authors: Agnès Poirier, Marla Weetall, Katja Heinig, Franz Bucheli, Kerstin Schoenlein, Jochem Alsenz, Simon Bassett, Mohammed Ullah, Claudia Senn, Hasane Ratni, Nikolai Naryshkin, Sergey Paushkin, Lutz Mueller

Oral administration of the selective GPR120/FFA4 agonist compound A is not effective in alleviating tissue inflammation in mouse models of prototypical autoimmune diseases

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Article date: December 2018

Authors: Melanie Wannick, Siegfried Bezdek, Nathalie Guillen, Markus Thieme, Fibi Meshrkey, Sadegh Mousavi, Michaela Seeling, Falk Nimmerjahn, Attila Mócsai, Detlef Zillikens, Tanya Sezin, Christian D. Sadik

A comparison of biological activity of commercially available purified native botulinum neurotoxin serotypes A1 to F1 in vitro, ex vivo, and in vivo

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Article date: December 2018

Authors: Sarah Donald, Mark Elliott, Bryony Gray, Fraser Hornby, Agnieszka Lewandowska, Sandra Marlin, Christine Favre‐Guilmard, Cindy Périer, Sylvie Cornet, Mikhail Kalinichev, Johannes Krupp, Elena Fonfria

Polypharmacy and medication deprescribing: A survey among multimorbid older adults in Denmark

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Article date: December 2018

Authors: Michaela L. Schiøtz, Anne Frølich, Anette K. Jensen, Lene Reuther, Hans Perrild, Tonny S. Petersen, Jonatan Kornholt, Mikkel B. Christensen

Issue Information

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Article date: December 2018

Efficacy of SMTP‐7, a small‐molecule anti‐inflammatory thrombolytic, in embolic stroke in monkeys

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Article date: December 2018

Authors: Eriko Suzuki, Naoko Nishimura, Tetsuya Yoshikawa, Yudai Kunikiyo, Keiko Hasegawa, Keiji Hasumi