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Pharmacology Research & Perspectives

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Mutagenesis of GPR139 reveals ways to create gain or loss of function receptors

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Article date: February 2019

Authors: Lien Wang, Grace Lee, Amy Shih, Chester Kuei, Diane Nepomuceno, Michelle Wennerholm, Frances Fan, Jiejun Wu, Pascal Bonaventure, Timothy W. Lovenberg, Changlu Liu

Diazepam is not a direct allosteric modulator of α1‐adrenoceptors, but modulates receptor signaling by inhibiting phosphodiesterase‐4

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Article date: February 2019

Authors: Lisa M. Williams, Xiaoji He, Tasneem M. Vaid, Alaa Abdul‐Ridha, Alice R. Whitehead, Paul R. Gooley, Ross A.D. Bathgate, Spencer J. Williams, Daniel J. Scott

Treatment with new organic nitrites in pulmonary hypertension of acute experimental pulmonary embolism

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Article date: February 2019

Authors: Kristofer F. Nilsson, Lars E. Gustafsson

pH as a potential therapeutic target to improve temozolomide antitumor efficacy : A mechanistic modeling study

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Article date: February 2019

Authors: Angélique Stéphanou, Annabelle Ballesta

Frequency and predictors of the potential overprescribing of antidepressants in elderly residents of a geographically defined U.S. population

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Article date: February 2019

Authors: William V. Bobo, Brandon R. Grossardt, Maria I. Lapid, Jonathan G. Leung, Cynthia Stoppel, Paul Y. Takahashi, Robert W. Hoel, Zheng Chang, Christian Lachner, Mohit Chauhan, Lee Flowers, Scott M. Brue, Mark A. Frye, Jennifer St. Sauver, Walter A. Rocca, Bruce Sutor

Development and validation of PART (Pharmacotherapy Assessment in Renal Transplant Patients) criteria to assess drug‐related problems in an outpatient renal transplant population: A cross‐sectional study

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Article date: February 2019

Authors: Layal El Raichani, Qian Du, Alexandre Mathieu, Sabrina Almassy, Lyne Lalonde, Djamal Berbiche, Elisabeth Gélinas‐Lemay, Nathalie Boudreau, Héloïse Cardinal

Combined antitumoral effects of pretubulysin and methotrexate

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Article date: February 2019

Authors: Sarah Kern, Ines Truebenbach, Miriam Höhn, Jan Gorges, Uli Kazmaier, Stefan Zahler, Angelika M. Vollmar, Ernst Wagner

Drug‐related teratogenic and pathologic causes of birth defects in a tertiary hospital in Southwestern Nigeria

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Article date: February 2019

Authors: Ifeanyichukwu Offor, Olufunsho Awodele, Kazeem A. Oshikoya

Medical simulation in pharmacology learning and retention: A comparison study with traditional teaching in undergraduate medical students

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Article date: February 2019

Authors: Vincenzo Arcoraci, Francesco Squadrito, Domenica Altavilla, Alessandra Bitto, Letteria Minutoli, Olivia Penna, Antonio Amato, Rosario Bruno, Vincenzo Francesco Tripodi, Angela Alibrandi, Pier Luigi Ingrassia, Paola Santalucia, Vincenzo Fodale

Pharmacokinetics and safety of Enasidenib following single oral doses in Japanese and Caucasian subjects

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Article date: December 2018

Authors: Yan Li, Liangang Liu, Diana Gomez, Jian Chen, Zeen Tong, Maria Palmisano, Simon Zhou