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Pharmacology Research & Perspectives

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Drug‐related teratogenic and pathologic causes of birth defects in a tertiary hospital in Southwestern Nigeria

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Article date: February 2019

Authors: Ifeanyichukwu Offor, Olufunsho Awodele, Kazeem A. Oshikoya

Medical simulation in pharmacology learning and retention: A comparison study with traditional teaching in undergraduate medical students

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Article date: February 2019

Authors: Vincenzo Arcoraci, Francesco Squadrito, Domenica Altavilla, Alessandra Bitto, Letteria Minutoli, Olivia Penna, Antonio Amato, Rosario Bruno, Vincenzo Francesco Tripodi, Angela Alibrandi, Pier Luigi Ingrassia, Paola Santalucia, Vincenzo Fodale

Post‐MI treatment with G‐CSF and EPO‐liposome with SLX repairs infarcted myocardium through EPCs mobilization and activation of prosurvival signals in rabbits

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Article date: February 2019

Authors: Yoshihisa Yamada, Shingo Minatoguchi, Noriko Endo, Hiromitsu Kanamori, Masanori Kawasaki, Kazuhiko Nishigaki, Atsushi Mikami, Shinya Minatoguchi

A pharmacokinetic study of radiprodil oral suspension in healthy adults comparing conventional venous blood sampling with two microsampling techniques

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Article date: February 2019

Authors: David Sciberras, Christian Otoul, Françoise Lurquin, John Smeraglia, Aurélia Lappert, Steven De Bruyn, Jan Jaap van Lier

MDM2 inhibitor ameliorates cisplatin‐induced nephropathy via NFκΒ signal inhibition

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Article date: February 2019

Authors: Tomoyuki Fujikura, Hideo Yasuda, Takamasa Iwakura, Takayuki Tsuji, Hans‐J. Anders

Binding characterization of N‐(2‐chloro‐5‐thiomethylphenyl)‐N′‐(3‐[3H]3methoxy phenyl)‐N′‐methylguanidine ([3H]GMOM), a non‐competitive N‐methyl‐D‐aspartate (NMDA) receptor antagonist

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Article date: February 2019

Authors: Athanasios Metaxas, Bart N. M. van Berckel, Pieter J. Klein, Joost Verbeek, Emily C. Nash, Esther J. M. Kooijman, Véronique A. Renjaän, Sandeep S. V. Golla, Ronald Boellaard, Johannes A. M. Christiaans, Albert D. Windhorst, Josée E. Leysen

Issue Information

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Article date: February 2019

Memantine protects thalamocortical hyper‐glutamatergic transmission induced by NMDA receptor antagonism via activation of system xc

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Article date: February 2019

Authors: Motohiro Okada, Kouji Fukuyama, Yasuhiro Kawano, Takashi Shiroyama, Yuto Ueda

Phase I study of PF‐04895162, a Kv7 channel inhibitor, reveals unexpected hepatotoxicity in healthy subjects, but not rats or monkeys: clinical evidence of disrupted bile acid homeostasis

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Article date: February 2019

Authors: Michael D. Aleo, Jiri Aubrecht, Paul D. Bonin, Deborah A. Burt, Jennifer Colangelo, Lina Luo, Shelli Schomaker, Rachel Swiss, Simon Kirby, Greg C. Rigdon, Pinky Dua

Preclinical tissue distribution and metabolic correlations of vigabatrin, an antiepileptic drug associated with potential use‐limiting visual field defects

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Article date: February 2019

Authors: Dana C. Walters, Erwin E. W. Jansen, Garrett R. Ainslie, Gajja S. Salomons, Madalyn N. Brown, Michelle A. Schmidt, Jean‐Baptiste Roullet, K. M. Gibson