Pharmacology Research & Perspectives

Exploring the overlapping binding sites of ifenprodil and EVT‐101 in GluN2B‐containing NMDA receptors using novel chicken embryo forebrain cultures and molecular modeling

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Article date: June 2019

Authors: Marthe F. Fjelldal, Thibaud Freyd, Linn M. Evenseth, Ingebrigt Sylte, Avi Ring, Ragnhild E. Paulsen

Leucine‐rich repeat kinase 2 (LRRK2) inhibitors differentially modulate glutamate release and Serine935 LRRK2 phosphorylation in striatal and cerebrocortical synaptosomes

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Article date: June 2019

Authors: Daniela Mercatelli, Paolo Bolognesi, Martina Frassineti, Clarissa A. Pisanò, Francesco Longo, Derya R. Shimshek, Michele Morari

Health professionals’ and researchers’ opinions on conducting clinical deprescribing trials

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Article date: June 2019

Authors: Alexander J. Clough, Sarah N. Hilmer, Lisa Kouladjian‐O'Donnell, Sharon L. Naismith, Danijela Gnjidic

Issue Information

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Article date: June 2019

Histidine‐rich glycoprotein augments natural killer cell function by modulating PD‐1 expression via CLEC‐1B

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Article date: June 2019

Authors: Yoshito Nishimura, Hidenori Wake, Kiyoshi Teshigawara, Dengli Wang, Masakiyo Sakaguchi, Fumio Otsuka, Masahiro Nishibori

The effect of chronic kidney disease on CYP2B expression and activity in male Wistar rats

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Article date: June 2019

Authors: Andrew S. Kucey, Thomas J. Velenosi, Nicholas C. Tonial, Alvin Tieu, Adrien A. E. RaoPeters, Brad L. Urquhart

Prescribing trend in cardiovascular patients at Ethiopian university hospital: The number of medications and implication on the clinical improvement

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Article date: June 2019

Authors: Yonas G. Tefera, Tamrat B. Abebe, Abebe B. Mekuria, Misganaw S. Kelkay, Tadesse M. Abegaz

Depressive disorders: Treatment failures and poor prognosis over the last 50 years

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Article date: June 2019

Authors: Thomas P. Blackburn

Target validation: Weak selectivity of LY341495 for mGluR2 over mGluR4 makes glutamate a less selective agonist

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Article date: June 2019

Authors: Tyler W. McCullock, Paul J. Kammermeier

Application of ultrasound‐guided cholecystocentesis to the evaluation of the metabolite profiling in bile of dogs and cynomolgus monkeys

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Article date: June 2019

Authors: Elizabeth A. Dierks, Chiuwa E. Luk, Hong Cai, Jamus MacGuire, Maxine Fox, James Smalley, R. Marc Fancher, Evan Janovitz, Kimberly Foster, Qin Sun