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Pharmacology Research & Perspectives

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Inconsistencies in dosage practice in children with overweight or obesity: A retrospective cohort study

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Article date: June 2018

Authors: Christina Gade, Hanne R. Christensen, Kim P. Dalhoff, Jens Christian Holm, Helle Holst

Enantioselectivity in the tissue distribution of perhexiline contributes to different effects on hepatic histology and peripheral neural function in rats

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Article date: June 2018

Authors: Giovanni Licari, Robert W. Milne, Andrew A. Somogyi, Benedetta C. Sallustio

Effect of a mitochondrial‐targeted coenzyme Q analog on pancreatic β‐cell function and energetics in high fat fed obese mice

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Article date: June 2018

Authors: Yumi Imai, Brian D. Fink, Joseph A. Promes, Chaitanya A. Kulkarni, Robert J. Kerns, William I. Sivitz

Propranolol pharmacokinetics in infants treated for Infantile Hemangiomas requiring systemic therapy: Modeling and dosing regimen recommendations

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Article date: June 2018

Authors: Laurence Del Frari, Christine Léauté‐Labrèze, Laurent Guibaud, Sébastien Barbarot, Jean‐Philippe Lacour, Christine Chaumont, Alain Delarue, Jean‐Jacques Voisard, Valérie Brunner

Effects of magnesium chloride on in vitro cholinesterase and ATPase poisoning by organophosphate (chlorpyrifos)

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Article date: June 2018

Authors: Bamidele S. Ajilore, Adetayo A. Alli, Tolulope O. Oluwadairo

Pharmacokinetics, safety, and tolerability of the 2‐ and 3‐direct‐acting antiviral combination of AL‐335, odalasvir, and simeprevir in healthy subjects

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Article date: June 2018

Authors: Thomas N. Kakuda, Matthew W. McClure, Christopher Westland, Jennifer Vuong, Marie‐Claude Homery, Gwendoline Poizat, Laure Viguerie, Caroline Denot, Alain Patat, Qingling Zhang, James Hui, David Apelian, David B. Smith, Sushmita M. Chanda, John Fry

Pharmacokinetics and pharmacodynamics of the cytolytic anti‐CD38 human monoclonal antibody TAK‐079 in monkey – model assisted preparation for the first in human trial

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Article date: June 2018

Authors: Stefan Roepcke, Nele Plock, Josh Yuan, Eric R. Fedyk, Gezim Lahu, Lin Zhao, Glennda Smithson

No effect of thymosin beta‐4 on the expression of the transcription factor Islet‐1 in the adult murine heart

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Article date: June 2018

Authors: Florian Weinberger, Philipp Nicol, Jutta Starbatty, Mandy Stubbendorff, Peter M. Becher, Sonja Schrepfer, Thomas Eschenhagen

Direct and cytokine‐mediated effects of albumin‐fused growth hormone, TV‐1106, on CYP enzyme expression in human hepatocytes in vitro

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Article date: June 2018

Authors: Maciej Czerwiński, Immaculate Amunom, Victor Piryatinsky, Hussein Hallak, Yousif Sahly, Oren Bar‐Ilan, Paul Bolliger, Merav Bassan

Expression of cytochrome P450 mRNAs in Type II alveolar cells from subjects with chronic obstructive pulmonary disease

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Article date: June 2018

Authors: Satoshi Kamata, Naoya Fujino, Mitsuhiro Yamada, Ken Grime, Satoshi Suzuki, Chiharu Ota, Yukiko Tando, Yoshinori Okada, Akira Sakurada, Masafumi Noda, Yasushi Matsuda, Hisatoshi Sugiura, Masakazu Ichinose