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British Journal of Pharmacology


Efficacious dose of metformin for breast cancer therapy is determined by cation transporter expression in tumours

Pages: 2724-2735

Article date: August 2019

Authors: Hao Cai, Ruth S. Everett, Dhiren R. Thakker

Blockade of the forward Na+/Ca2+ exchanger suppresses the growth of glioblastoma cells through Ca2+‐mediated cell death

Pages: 2691-2707

Article date: August 2019

Authors: Hui‐Jie Hu, Shan‐Shan Wang, Yan‐Xia Wang, Yan Liu, Xue‐Mei Feng, Ying Shen, Liang Zhu, Hong‐Zhuan Chen, Mingke Song

Strain‐selective efficacy of sacubitril/valsartan on carotid fibrosis in response to injury in two inbred mouse strains

Pages: 2795-2807

Article date: August 2019

Authors: Vyacheslav A. Korshunov, Breandan Quinn, Abrar Faiyaz, Rifat Ahmed, Mark P. Sowden, Marvin M. Doyley, Bradford C. Berk

Histidine‐rich glycoprotein ameliorates endothelial barrier dysfunction through regulation of NF‐κB and MAPK signal pathway

Pages: 2808-2824

Article date: August 2019

Authors: Shangze Gao, Hidenori Wake, Yuan Gao, Dengli Wang, Shuji Mori, Keyue Liu, Kiyoshi Teshigawara, Hideo Takahashi, Masahiro Nishibori

Early toll‐like receptor 4 blockade reduces ROS and inflammation triggered by microglial pro‐inflammatory phenotype in rodent and human brain ischaemia models

Pages: 2764-2779

Article date: August 2019

Authors: Esther Parada, Ana I. Casas, Alejandra Palomino‐Antolin, Vanessa Gómez‐Rangel, Alfonso Rubio‐Navarro, Victor Farré‐Alins, Paloma Narros‐Fernandez, Melania Guerrero‐Hue, Juan Antonio Moreno, Juliana M. Rosa, José M. Roda, Borja J. Hernández‐García, Javier Egea

Histidine at position 462 determines the low quinine sensitivity of ether‐à‐go‐go channel superfamily member Kv12.1

Pages: 2708-2723

Article date: August 2019

Authors: Marlen Dierich, Willem B. Ham, Anna Stary‐Weinzinger, Michael G. Leitner

Ursodeoxycholic acid accelerates bile acid enterohepatic circulation

Pages: 2848-2863

Article date: August 2019

Authors: Yunjing Zhang, Runqiu Jiang, Xiaojiao Zheng, Sha Lei, Fengjie Huang, Guoxiang Xie, Sandi Kwee, Herbert Yu, Christine Farrar, Beicheng Sun, Aihua Zhao, Wei Jia

Molecular dynamics simulations of dihydro‐β‐erythroidine bound to the human α4β2 nicotinic acetylcholine receptor

Pages: 2750-2763

Article date: August 2019

Authors: Rilei Yu, Han‐Shen Tae, Qingliang Xu, David J. Craik, David J. Adams, Tao Jiang, Quentin Kaas

A photoswitchable GABA receptor channel blocker

Pages: 2661-2677

Article date: August 2019

Authors: Galyna Maleeva, Daniel Wutz, Karin Rustler, Alba Nin‐Hill, Carme Rovira, Elena Petukhova, Antoni Bautista‐Barrufet, Alexandre Gomila‐Juaneda, Petra Scholze, Franck Peiretti, Mercedes Alfonso‐Prieto, Burkhard König, Pau Gorostiza, Piotr Bregestovski