ANTIPHLOGISTIC ACTIVITY OF IPRONIAZID

Article date: December 1959

By: I. SETNIKAR, M. SALVATERRA, O. TEMELCOU in Volume 14, Issue 4, pages 484-487

Iproniazid was found to inhibit formalin‐induced oedema of the foot, dextran‐induced oedema and cotton‐pellet‐induced granulomatous tissue in the rat. The presence of the adrenals was essential for the antiphlogistic activity. The antiphlogistic action was not accompanied by any antipyretic effect. Inhibition of formalin‐induced oedema was also observed with phenylbutazone and with salicylamide.

DOI: 10.1111/j.1476-5381.1959.tb00952.x

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