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British Journal of Clinical Pharmacology


Assessing the impact of the addition of dendritic cell vaccination to neoadjuvant chemotherapy in breast cancer patients: A model‐based characterization approach

Pages: 1670-1683

Article date: August 2019

Authors: Belén P. Solans, Ascensión López‐Díaz de Cerio, Arlette Elizalde, Luis Javier Pina, Susana Inogés, Jaime Espinós, Esteban Salgado, Luis Daniel Mejías, Iñaki F. Trocóniz, Marta Santisteban

Warfarin dose requirement in patients having severe thrombosis or thrombophilia

Pages: 1684-1691

Article date: August 2019

Authors: Tuukka A. Helin, Lotta Joutsi‐Korhonen, Heidi Asmundela, Mikko Niemi, Arto Orpana, Riitta Lassila

Chronotherapy as a potential approach to hypertensive patients with elevated heart rate?

Pages: 1861-1862

Article date: August 2019

Authors: Fedor Simko, Tomas Baka

Population pharmacokinetic model and Bayesian estimator for 2 tacrolimus formulations in adult liver transplant patients

Pages: 1740-1750

Article date: August 2019

Authors: Camille Riff, Jean Debord, Caroline Monchaud, Pierre Marquet, Jean‐Baptiste Woillard

Investigation of the absolute bioavailability and human mass balance of navoximod, a novel IDO1 inhibitor

Pages: 1751-1760

Article date: August 2019

Authors: Shuguang Ma, Julia Suchomel, Evelyn Yanez, Edward Yost, Xiaorong Liang, Rui Zhu, Hoa Le, Nicholas Siebers, Lori Joas, Roland Morley, Stephanie Royer‐Joo, Andrea Pirzkall, Laurent Salphati, Joseph A. Ware, Kari M. Morrissey

Methadone and buprenorphine pharmacokinetics and pharmacodynamics when coadministered with fostemsavir to opioid‐dependent, human immunodeficiency virus seronegative participants

Pages: 1771-1780

Article date: August 2019

Authors: Katy Moore, Mindy Magee, Heather Sevinsky, Ming Chang, Susan Lubin, Elsa Myers, Peter Ackerman, Cyril Llamoso

Dynamics of circulating vascular endothelial growth factor‐A predict benefit from antiangiogenic cediranib in metastatic or recurrent cervical cancer patients

Pages: 1781-1789

Article date: August 2019

Authors: Cong Zhou, Sarah Taylor, Jonathan Tugwood, Kathryn Simpson, Gordon C. Jayson, Paul Symonds, James Paul, Susan Davidson, Karen Carty, Elaine McCartney, Debbie Rai, Caroline Dive, Catharine West

Body of evidence and approaches applied in the clinical development programme of fixed‐dose combinations in the European Union from 2010 to 2016

Pages: 1829-1840

Article date: August 2019

Authors: Asbjørn Nøhr‐Nielsen, Marie Louise De Bruin, Mikael Thomsen, Christian Bressen Pipper, Theis Lange, Ole Jannik Bjerrum, Trine Meldgaard Lund

Erlotinib treatment induces cytochrome P450 3A activity in non‐small cell lung cancer patients

Pages: 1704-1709

Article date: August 2019

Authors: Anna Svedberg, Svante Vikingsson, Anders Vikström, Niels Hornstra, Magnus Kentson, Eva Branden, Hirsh Koyi, Bengt Bergman, Henrik Gréen