Article date: November 1986
By: BF Johnson, V Shekar, T Woodman, AT Canada, in Volume 22, Issue 5, pages 613-615
Salivary concentrations of the anti‐arrhythmic, pirmenol, were compared with plasma concentrations in six patients. Group mean salivary values tended to be higher despite high plasma protein binding, suggesting the possibility of an active transport process. The observed salivary concentrations are reasonably close to those detectable in healthy volunteers as tasting unpleasant.
DOI: 10.1111/j.1365-2125.1986.tb02944.x
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