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British Journal of Clinical Pharmacology

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Pharmacological vs. classical approaches in the design of first in man clinical drug trials

Pages: 2807-2812

Article date: December 2017

Authors: Cornelis A. Bogert, Adam F. Cohen, Hubert G. M. Leufkens, Joop M. A. Gerven

Issue Information

Pages: 2591-2592

Article date: December 2017

Population pharmacokinetics and electrocardiographic effects of dihydroartemisinin–piperaquine in healthy volunteers

Pages: 2752-2766

Article date: December 2017

Authors: Palang Chotsiri, Thanaporn Wattanakul, Richard M. Hoglund, Borimas Hanboonkunupakarn, Sasithon Pukrittayakamee, Daniel Blessborn, Podjanee Jittamala, Nicholas J. White, Nicholas P.J. Day, Joel Tarning

High‐risk prescribing in an Irish primary care population: trends and variation

Pages: 2821-2830

Article date: December 2017

Authors: Catherine J. Byrne, Caitriona Cahir, Carmel Curran, Kathleen Bennett

Use of junior doctor‐led peer education to improve antibiotic stewardship

Pages: 2831-2832

Article date: December 2017

Authors: Eugene Y. H. Yeung, Megan Alexander

Pharmacokinetics and safety of the anti‐human cytomegalovirus drug letermovir in subjects with hepatic impairment

Pages: 2678-2686

Article date: December 2017

Authors: Dirk Kropeit, David McCormick, Katharina Erb‐Zohar, Valentin S. Moiseev, Zhanna D. Kobalava, Hans‐Peter Stobernack, Holger Zimmermann, Helga Rübsamen‐Schaeff

Ticagrelor mitigates ischaemia–reperfusion induced vascular endothelial dysfunction in healthy young males – a randomized, single‐blinded study

Pages: 2651-2660

Article date: December 2017

Authors: Stefan Weisshaar, Brigitte Litschauer, Matthias Eipeldauer, Eva Luise Hobl, Michael Wolzt

Effect of gemfibrozil and rifampicin on the pharmacokinetics of selexipag and its active metabolite in healthy subjects

Pages: 2778-2788

Article date: December 2017

Authors: Shirin Bruderer, Marc Petersen‐Sylla, Margaux Boehler, Tatiana Remeňová, Atef Halabi, Jasper Dingemanse

Issue highlights

Pages: 2593-2594

Article date: December 2017

The acute effect of beta‐guanidinopropionic acid versus creatine or placebo in healthy men (ABC‐Trial): A randomized controlled first‐in‐human trial

Pages: 2626-2635

Article date: December 2017

Authors: Fares A. Karamat, Deborah L. Horjus, Yentl C. Haan, Lisa Woude, Marianne C. Schaap, Inge Oudman, Gert A. Montfrans, Rienk Nieuwland, Gajja S. Salomons, Joseph F. Clark, Lizzy M. Brewster