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Pharmacokinetics and Pharmacodynamics (PKPD) 2017 workshop

The Society's workshops are usually suitable for Masters level and above, and can be taken as part of the Diploma in Advanced Pharmacology. Basic pharmacological knowledge is expected.

11–12 Sep 2017

Abstracts deadline:

Registration deadline:

London, UK - View map

  • Overview
  • Programme
  • Social programme
  • Registration
  • Venue
This workshop covers the fundamental aspects of pharmacokinetics and pharmacodynamics. The workshop takes the format of lectures introducing concept, basic theory and practical examples reinforced with tutorials on data analysis and modelling and simulation. Students will be expected to play an active role (a calculator is required) in analysis, interpretation and discussion.

Learning outcomes

The workshop will deliver the following learning outcomes:

  • Introduction to the fundamental principles of pharmacokinetic (PK) and pharmacodynamic (PD) data analysis
  • Consideration of other contributory factors and processes that influence PK and PD measurements and outcome
  • Appreciation and understanding of the importance and contribution of PKPD by first intent to inform preclinical and clinical study design

Speaker information

Dr Neil Upton: A behavioural Pharmacologist with over 25 years in major Pharma (GlaxoSmithKline) leading multidisciplinary teams of up to 40 preclinical and clinical translational scientists specializing in diverse CNS indications including Alzheimer’s disease, schizophrenia, pain, epilepsy and affective and sleep disorders. Neil is an expert in designing preclinical pharmacokinetic-pharmacodynamic studies to aid clinical dose selection and target therapeutic indication(s) for new molecular entities. He has an extensive drug discovery know-how ranging from target identification/validation through to late stage Project leadership including design of Phase I & II clinical protocols. Neil has a strong track record of delivering development quality candidates – five successful Proof of Concept molecules to date. He is a lead investigator on a portfolio of multi-million euro industry-academia collaborations to identify new translational markers for cognitive enhancers and has 100+ papers and is an inventor on five patents and author of numerous regulatory reports.

Dr Phil Jeffrey: Head of Translational Sciences in the Rare Diseases Research Unit at Pfizer and joined the group in January 2014. Phil has over 30 years’ experience in the pharmaceutical industry and has a successful track record in drug discovery from early lead optimisation through to clinical proof of mechanism and proof of concept. Phil has a PhD in drug metabolism and pharmacokinetics from the University of Sheffield and has worked for The Upjohn Company, SmithKline Beecham and GlaxoSmithKline across a wide variety of therapeutic areas including; auto-immunity, inflammation, CNS, anti-infectives, epigenetics, cardiovascular and rare diseases. Authored/co-authored over 50 papers and four book chapters. Phil’s current scientific interests include “engineering biology” and predicting clinical pharmacokinetics and pharmacodynamics response from preclinical data.

James Clarke: Holds an MSc in Biochemistry from the University of Kent. James has 14 years’ postgraduate experience in the pharmaceutical industry across multiple disease areas within Pfizer, GSK, Shire, BTG and more recently AstraZeneca. James has held roles in drug target validation and clinical pharmacology but the majority of his career has been within DMPK supporting clinical development. In his current role, James performs the function of a DMPK Project Leader in an oncology therapy area, supporting drug development projects from candidate selection to product lifecycle.

Dr Pinky Dua: Senior Director of Clinical Pharmacology at Pfizer and is the Head of Clinical Pharmacology for the Rare Disease research unit. Pinky has over 10 years’ experience in the pharmaceutical industry and has strong scientific and technical background with proven track record in quantitative modelling and simulation for drug discovery and development. Pinky has worked across a wide variety of therapeutic areas – Pain, Neurology, Psychiatry, Respiratory, GI and Rare Diseases. Pinky has a PhD in Chemical Engineering from Imperial College London, has published over 20 journal and conference papers and six book chapters. Pinky has delivered invited/plenary talks at international pharmaceutical conferences and at academic institutions.
 
Rob Willis: Investigator, Quantitative Pharmacology, Immuno-Inflammation therapy area, GSK, providing strategic DMPK input as part of a multi-functional lead optimisation drug discovery programme team. In his role, Rob is responsible for the design and implementation of key DMPK and in vivo efficacy studies to evaluate molecules from start of chemistry through lead optimisation to candidate selection. He has worked at GSK for 13 years providing DMPK input to early stage discovery programmes across a number of therapy areas. He is experienced in PK, PK/PD and PBPK modelling including human PK and efficacious dose predictions from preclinical data. Rob is in his final year of a part time PhD investigating PK/PD modelling of acute inflammatory challenge models. 

Workshop dinner

A workshop dinner for speakers and delegates will be held on Monday 11 September. This is an excellent opportunity to meet and network with both the speakers and other delegates in an informal setting.

Venue:
Albertini
16-20 Chalton Street
London
NW1 1JH

Registration fees

Registration is now fully booked. For further information please contact meetings@bps.ac.uk

Registration fees include attendance to the workshop and refreshments.
 
  Early-bird rates Standard rate
BPS Member Registration £100 £150
Non-Member Registration £150 £200
Delegate dinner  N/A £25

Workshop venue

Thistle Hotel
Cardington Street
Euston
NW1 2LP

Travel information:

Rail/Tube:

London Euston mainline and Underground (Northern and Victoria lines) stations are a 200-metre walk from the hotel. Consult the Transport for London website for further details.

Bus:
The closest bus stops to the hotel, you can find the number 29, 88, 24 that goes to the city centre. There are plenty more options at Euston Station which is just 5 minutes walking from the hotel.

By Car:
From the Euston Road (A501), turn into Melton Street (on the west side of the station), which becomes Cardington Street; Thistle Euston is situated on the left. To programme your sat-nav, please use the postcode NW1 2LP.

Car parking:
The nearest parking availabe is at the Ibis Hotel, which is next door to the Thistle Hotel. There is also parking available at Euston Station.

Taxi:
If you require a taxi, the 24-hour reception at the Thistle Hotel are happy to assist you in booking one.

By Air:
From London Heathrow, the Heathrow Express runs direct to London Paddington in just 15 minutes (20 from Terminal 5), with a train every quarter of an hour. The Gatwick Express runs a similar service into London Victoria from London Gatwick.

Tourist information
London's primary Tourist Information Centre is: Victoria Station Travel Information Centre, Opposite platform 8, Victoria Railway Station, London, SW1V 1JU, Tube: Victoria
For further information about London and locations of other tourist information, please visit their website.

British Pharmacological Society on-site contact details
Laura Neville – Education & Training Manager
Email: laura.neville@bps.ac.uk        
Mobile: +44 (0) 7789 076273