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Clinical Pharmacometrician (Associate or Senior)

Job reference:R-092724

Location:Waltham, MA (USA)

Category:Latest jobs

Closing date:

Start date:

Contact:Karthick Vishwanathan (Karthick.vishwanathan@astrazeneca.com)

AstraZeneca


Do you have experience in the clinical pharmacometric aspects of drug development, with model-informed drug development?

AstraZeneca is seeking a proven Clinical Pharmacometrician that will support small and large molecule projects within Oncology.

At AstraZeneca, we win through science, it’s at the heart of our every success. That science is only possible when we all work together – we’ll always make sure you’re clear about how your role is connected to our wider mission to really show what science can do!


As a Clinical Pharmacometrician you will work closely with physicians, clinical pharmacology scientists and statisticians, you’ll be responsible for population PK, PKPD, exposure-response, disease modelling and simulation (M&S) efforts to support the design and interpretation of clinical studies, influence key decisions in the early and late clinical development and support regulatory submissions of our Oncology medicines.

As the Clinical Pharmacometrician, your work includes integration and analysis of pharmacokinetic, biomarker and clinical endpoint data within and across studies, compounds and development stages. Input into trial designs using simulations and efficient modeling statistics is an important focus area for us. In collaboration with clinical pharmaology scientists, you’ll represent CPQP on projects and contribute to the clinical pharmacology and pharmacometric strategy. You will communicate your findings to other scientists within AstraZeneca with the opportunity and expectation to present externally and publish in peer reviewed journals.

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