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Dr R. John Dobbs MC FRCP

Dr R. John Dobbs MC FRCP

Name:

Dr R. John Dobbs MC FRCP FBPhS

Organisation:

Institute of Pharmaceutical Science, King’s College London

Year elected:

2012

Primary professional setting:

Academia

Graduated in medicine from the University of Manchester. Trained in Clinical Pharmacology, UCL (BNC Prichard, JW Black) and St George’s (HP Rang) Later Consultant Physician MRC Clinical Research Centre, Harrow. Currently Senior Clinical Researcher, KCL. The aim, with Sylvia Dobbs, is an aetiopathogenic model for Parkinson’s disease (PD) and co-morbidities, taking into account the pre-clinical/prodromal ‘submerged iceberg’. We go beyond clinical diagnostic/severity scores, extending measures of facets, objective where possible, into ‘controls’. (We have evidence that PD-probands’ spouses are down-the-way towards PD.) We are using quantitative metagenomics to investigate species/strains with altered abundance associated with disease facets, metabolomics and immunobiology to define putative mediators/pathways, stratifying for human risk/immune-inflammatory genetics.