Bharath Srinivasan

Bharath Srinivasan studied the structure-function relationship in members of the Haloacid Dehalogenase superfamily of enzymes as part of his PhD studies. He pursued an NIH-sponsored postdoctoral fellowship at the Centre for the Study of Systems Biology, Georgia Institute of Technology, working at the interface between enzyme kinetics, computational sciences and medicinal chemistry. Subsequently, he was awarded the prestigious Marie Skłodowska-Curie Actions fellowship to study the substrate specificity of deaminases acting on double-stranded RNA at the Instituto Gulbenkian de Ciencia, Portugal. In 2019, he joined the Mechanistic Biology and Profiling unit at AstraZeneca, contributing actively to several oncology projects deducing the MoA of small-molecule leads. Bharath has published around 40 peer-reviewed publications, 1 patent and several science outreach articles. He is editor with two prominent pharmacology journals (British Journal of Pharmacology and Current opinion in Pharmacology), a faculty with H1 connect and on the editorial advisory board of FEBS J. He is an honorary Associate Professor at the Robert Gordon University, Scotland. He is passionate about enzyme kinetics with particular emphasis on studying the spatio-temporal evolution of kinetic systems, steady state kinetics, pre-steady state kinetics, single turnover kinetics and non-Michaelian kinetics. Bharath is also invested heavily in optimizing methods for in-cellulo kinetics and label-free detection methods.