The Guide to Pharmacology is a new online database which acts as a “one-stop shop” source of quantitative information on drug targets and the prescription medicines and experimental drugs that act on them. The site has been created in collaboration between The British Pharmacological Society (BPS) and the International Union of Basic and Clinical Pharmacology (IUPHAR).

The Guide to Pharmacology will be useful for researchers and students in pharmacology and drug discovery, and will provide the general public with accurate information on the basic science underlying drug action. It provides a single entry point to:


  A searchable online database of information from the 5th (2011) edition of the BPS Guide to Receptors and Channels (GRAC), which provides a succinct overview of the key properties of over 1600 established or potential pharmacological targets. This online version of GRAC is enhanced with hyperlinks to additional information in the IUPHAR database, curated chemical structures and citations in PubMed.

   View the GRAC 5th edition table of contents.
   Read the GRAC 5th edition introduction for further information about GRAC.
   Download the GRAC 5th edition as a PDF.


  The IUPHAR database (IUPHAR-DB) provides in-depth coverage of the properties of G protein-coupled receptors (GPCRs), ion channels, and nuclear receptors and their ligands, intensively curated and peer-reviewed, with the chemical substances rigorously defined with molecular descriptors. 
Over time, these two separate resources will be integrated and expanded to include major areas of interest to pharmacology with links to other websites.

The Guide to Pharmacology is developed within the University/BHF Centre for Cardiovascular Science at the University of Edinburgh by the IUPHAR database team: Professor Tony Harmar, Dr Joanna Sharman, Dr Adam Pawson and Ms Helen Benson. Please email all enquiries to


 How to cite the data


 Visit the Guide to Pharmacology

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